| MANUFACTURING SERVICES | ANALYTICAL SERVICES | REGULATORY SERVICES |
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Compounding | Filling & Packaging | Unit-dose Liquids | Facilities Lyne's 115,000 square-foot facility was specifically designed and constructed for pharmaceutical manufacturing. Located on a five-acre campus in Brockton, Massachusetts, it is a modern, state-of-the-art facility. In a new modular explosion-proof building, Lyne is now able to manufacture large volumes of high-concentration flammable product. Tanks in the new tank farm handle batch sizes from 1000L up to 8000L. The manufacturing area contains 9 packaging and 6 compounding rooms. The packaging rooms are designed to house individual operations and are equipped with HEPA filters. The water system meets current USP specifications for purified water. Water is produced via various processes including reverse osmosis, deionization and filtration. The water is stored in a 2000 gallon holding tank and pumped through a recirculation loop. Water is filtered at all points of use. The equipment list is extensive for both clinical and commercial manufacturing. The following is a brief list of equipment at the facility: Various tanks from 100 L up to 10,000 L both jacketed Ribbon blenders Double cone and twin shell blenders Pfaudler rotary liquid filling National Instrument Monoblock liquid filling Norden Tube filling and cartoning Healthstar unit-dose liquid filler Lakso slat counters for tablets and capsules (various sizes) Mateer and Spee-Dee powder fillers
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